Anti-sodium Iodide Symprter

Description

The sodium iodide symporter (NIS) is an ion pump that actively transports iodide across the basolateral membrane into thyroid epithelial cells (1, 2). This is important step in the process of iodide organificaton and the formation of triiodothyronine and thyroxine (3). Mouse Anti-Human Sodium-Iodide Symporter Monoclonal IgG1 Kappa

Background

The sodium iodide symporter (NIS) is an ion pump that actively transports iodide across the basolateral membrane into thyroid epithelial cells (1, 2). This is important step in the process of iodide organificaton and the formation of triiodothyronine and thyroxine (3).

Host

Mouse

Clone

FP5

Isotype

IgG1 kappa

Immunogen

Mannose binding protein hNIS fusion (AA468-643)

Synonyms

NIS Antibody, SLC5A5 Antibody, solute carrier family 5 Antibody, Na (+)I(-) cotransporter Antibody

Specificity

Detects ~97kDa, non-glycosylated version at 68kDa. Other minor bands associated with hNIS at 160kDa, and degradation products at ~30 kDa, and ~15kDa.

Reactivity

Human, Mouse, Rat

Applications

AM, ICC, IF, IHC, WB

Form

Purified, in PBS pH7.4, 50% glycerol, 0.09% sodium azide

SwissProt

Q92911

Gene ID

NP_000444.1. 6528

Uniprot

Q92911